First Author | Matsui T | Year | 1993 |
Journal | FEBS Lett | Volume | 336 |
Issue | 1 | Pages | 107-10 |
PubMed ID | 7903253 | Mgi Jnum | J:16065 |
Mgi Id | MGI:64160 | Doi | 10.1016/0014-5793(93)81620-f |
Citation | Matsui T, et al. (1993) The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans. FEBS Lett 336(1):107-10 |
abstractText | Two newly identified human homeobox-containing genes, GBX1 and GBX2, are closely related genes, as are members of the other homeobox genes, EN-1 and EN-2. GBX1 and EN-2 have been mapped to chromosome 7q36. The present study shows that GBX2 was mapped to chromosome 2q37. EN-1 was mapped to chromosome 2q14. Moreover, two HOX complexes neighbored by the EVX gene, HOXA and HOXD, are located at chromosome 7p15-p14 and 2q31-q37, respectively. Thus, it is possible that these homeobox genes were linked to each other on an ancestral genome and that the ancestral chromosome segment was duplicated during evolution. |