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Publication : Characterization and mapping of the human SOX4 gene.

First Author  Farr CJ Year  1993
Journal  Mamm Genome Volume  4
Issue  10 Pages  577-84
PubMed ID  8268656 Mgi Jnum  J:15205
Mgi Id  MGI:63334 Doi  10.1007/BF00361388
Citation  Farr CJ, et al. (1993) Characterization and mapping of the human SOX4 gene. Mamm Genome 4(10):577-84
abstractText  The SOX genes comprise a large family related by homology to the HMG-box region of the testis-determining gene SRY. We have cloned and sequenced the human SOX4 gene. The open reading frame encodes a 474 amino acid protein, which includes an HMG-box. The non-box sequence is particularly rich in serine residues and has several polyglycine and polyalanine stretches. With somatic cell hybrids, human SOX4 has been mapped to Chromosome (Chr) 6p distal to the MHC region. There is no evidence for clustering of other members of the SOX1, -2, and -3 or SOX4 gene families around the SOX4 locus.
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