First Author | Jänne PA | Year | 1994 |
Journal | Cytogenet Cell Genet | Volume | 66 |
Issue | 3 | Pages | 164-6 |
PubMed ID | 8125013 | Mgi Jnum | J:17529 |
Mgi Id | MGI:65566 | Doi | 10.1159/000133691 |
Citation | Janne PA, et al. (1994) Localization of the 75-kDa inositol polyphosphate-5-phosphatase (INPP5B) to human chromosome band 1p34. Cytogenet Cell Genet 66(3):164-6 |
abstractText | The 75-kDa (type II) inositol polyphosphate-5-phosphatase, originally described in platelets, is one of at least three known enzymes capable of dephosphorylating inositol-1,4,5-trisphosphate (IP3) to inositol-1,4-bisphosphate (IP2). To further characterize these enzymatic forms, we have mapped the gene (INPP5B) coding for the 75-kDa type II enzyme. Using a combination of human x rodent somatic cell hybrids and fluorescence in situ hybridization, we have determined that this gene maps to human chromosome band 1p34. |