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Publication : Localization of the 75-kDa inositol polyphosphate-5-phosphatase (INPP5B) to human chromosome band 1p34.

First Author  Jänne PA Year  1994
Journal  Cytogenet Cell Genet Volume  66
Issue  3 Pages  164-6
PubMed ID  8125013 Mgi Jnum  J:17529
Mgi Id  MGI:65566 Doi  10.1159/000133691
Citation  Janne PA, et al. (1994) Localization of the 75-kDa inositol polyphosphate-5-phosphatase (INPP5B) to human chromosome band 1p34. Cytogenet Cell Genet 66(3):164-6
abstractText  The 75-kDa (type II) inositol polyphosphate-5-phosphatase, originally described in platelets, is one of at least three known enzymes capable of dephosphorylating inositol-1,4,5-trisphosphate (IP3) to inositol-1,4-bisphosphate (IP2). To further characterize these enzymatic forms, we have mapped the gene (INPP5B) coding for the 75-kDa type II enzyme. Using a combination of human x rodent somatic cell hybrids and fluorescence in situ hybridization, we have determined that this gene maps to human chromosome band 1p34.
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