First Author | Shamley DR | Year | 1993 |
Journal | J Endocrinol | Volume | 139 |
Issue | 3 | Pages | 473-8 |
PubMed ID | 8133214 | Mgi Jnum | J:17468 |
Mgi Id | MGI:65506 | Doi | 10.1677/joe.0.1390473 |
Citation | Shamley DR, et al. (1993) Maternal vitamin D status has no effect on the ontogeny of calcium-binding proteins in the duodenum, kidney and cerebellum of fetal mice. J Endocrinol 139(3):473-8 |
abstractText | The effects of vitamin D3 deficiency on the ontogeny of calcium-binding proteins (CaBPs) and the vitamin D receptor in the duodenum, kidney and cerebellum of the mouse were examined. Maternal vitamin D status did not affect the time of appearance of the fetal 28 kDa CaBP (CaBP-D28k) in the cerebellum, kidney and duodenum, and the 9 kDa CaBP (CaBP-D9k) in the intestine and kidney. Vitamin D receptor was undetectable in all fetal tissues, regardless of maternal vitamin D status, at all stages of gestation examined. Thus it appears that maternal vitamin D status does not affect the ontogeny of CaBP-D9k or CaBP-D28k in the mouse fetus. The factors that influence the appearance of calbindins in the fetus are unclear. |