| First Author | Imoto M | Year | 1994 |
| Journal | Exp Cell Res | Volume | 212 |
| Issue | 1 | Pages | 151-4 |
| PubMed ID | 7909754 | Mgi Jnum | J:18093 |
| Mgi Id | MGI:66112 | Doi | 10.1006/excr.1994.1129 |
| Citation | Imoto M, et al. (1994) Enhancement of CDP-DG:inositol transferase activity in src- and erbB2-transformed cells. Exp Cell Res 212(1):151-4 |
| abstractText | Phosphatidylinositol (PI) synthesis was activated in Rous sarcoma virus-infected NIH3T3 or activated erbB2-transformed NIH3T3 cells. The in vitro activity of CDP-DG:inositol transferase prepared from these cells was also higher than that from normal parent NIH3T3 cells, although phospholipase C and PI kinase activities were not significantly different among these cells. A tyrosine kinase inhibitor, erbstatin, inhibited the PI synthesis in cultured cells, suggesting that Src and ErbB2-associated tyrosine kinases are involved in activation of CDP-DG:inositol transferase in these cell lines. |
