| First Author | Müller B | Year | 1994 |
| Journal | Genomics | Volume | 20 |
| Issue | 2 | Pages | 317-9 |
| PubMed ID | 8020986 | Mgi Jnum | J:17419 |
| Mgi Id | MGI:65457 | Doi | 10.1006/geno.1994.1176 |
| Citation | Muller B, et al. (1994) Mapping of the autosomal dominant exudative vitreoretinopathy locus (EVR1) by multipoint linkage analysis in four families. Genomics 20(2):317-9 |
| abstractText | Autosomal dominant exudative vitreoretinopathy is a disorder affecting primarily the development of the human retinal vascular system. The disease locus has recently been assigned to 11q13-q23 by linkage studies in two families. Two-point analysis on a total of four families has now revealed close linkage (Zmax = 8.34 at theta = 0.00) between the disease locus and D11S873. Multipoint linkage analysis mapped the disease locus between D11S527/D11S533 and D11S35 with a maximum lod score of over 11 directly at D11S873. No evidence appeared for genetic/linkage heterogeneity among the four families examined. |
