| First Author | Frankel WN | Year | 1994 |
| Journal | Mamm Genome | Volume | 5 |
| Issue | 5 | Pages | 275-81 |
| PubMed ID | 8075500 | Mgi Jnum | J:18141 |
| Mgi Id | MGI:66156 | Doi | 10.1007/BF00389541 |
| Citation | Frankel WN, et al. (1994) Endogenous nonecotropic proviruses mapped with oligonucleotide probes from the long terminal repeat region [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome 5(5):275-81 |
| abstractText | We characterized endogenous proviruses in C57BL/6J, DBA/2J, and C3H/HeJ mouse strains with oligonucleotide probes derived from long terminal repeat (LTR) sequences of three classes of nonecotropic murine leukemia virus. The segregation of proviral-host DNA junction fragments was followed in BXH and BXD recombinant inbred (RI) strain sets, and most fragments mapped readily to defined chromosomal regions. Most of the LTR fragments appear to correspond to proviruses mapped previously with oligonucleotide env region probes of the same viral class. At least 22 elements represent new proviral loci, no more than half of which may be solo LTRs, and an additional six may correspond to proviruses identified previously with less specific hybridization probes. Together with proviruses identified previously with env probes, the LTR probe-reactive elements represent the majority of endogenous murine leukemia proviruses in the mouse genome. |
