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Publication : The expression of mouse T-cell receptor TCRDV genes in BALB/c spleen.

First Author  Wang K Year  1994
Journal  Immunogenetics Volume  40
Issue  4 Pages  271-9
PubMed ID  8082892 Mgi Jnum  J:20598
Mgi Id  MGI:68679 Doi  10.1007/BF00189972
Citation  Wang K, et al. (1994) The expression of mouse T-cell receptor TCRDV genes in BALB/c spleen. Immunogenetics 40(4):271-9
abstractText  The rearrangement and expression of six different mouse T-cell receptor TCRDV (V delta) gene subfamilies have been studied in BALB/c mouse spleen. The results show that all the TCRDV gene segments studied can be rearranged and expressed with both the TCRA (alpha) and the TCRD (delta) chain. The apparently restricted and separated V gene repertoire for the TCRD and TCRAT-cell receptor may result from thymus and peripheral selection rather than from selective rearrangement in the DNA level. Several J gene segments show much higher concentration in spleen with TCRDV gene segments, however, these J gene segments do not tend to be located at either end of the J gene cluster.
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