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Publication : Assignment of five loci from human chromosome 8q onto sheep chromosome 9.

First Author  Broad TE Year  1995
Journal  Cytogenet Cell Genet Volume  68
Issue  1-2 Pages  102-6
PubMed ID  7956345 Mgi Jnum  J:22103
Mgi Id  MGI:69686 Doi  10.1159/000133900
Citation  Broad TE, et al. (1995) Assignment of five loci from human chromosome 8q onto sheep chromosome 9. Cytogenet Cell Genet 68(1-2):102-6
abstractText  Using a chromosomally characterized minipanel of sheep x hamster cell hybrids, five new loci, including carbonic anhydrase II (CA2), calbindin 1 (28 kDa) (CALB1), corticotropin releasing hormone (CRH), cytochrome P450 11B subfamily XIB (steroid-11-beta-hydroxylase), polypeptide 1 (CYP11B1), and interleukin 7 (IL7), have been assigned to sheep chromosome 9. A homolog of CA2 was detected on sheep chromosome 1. CRH was regionally localized to sheep 9q23-->q28 by in situ hybridization. This study assigns chromosome 9 as the sheep equivalent of cattle chromosome 14 and indicates that CALB1, CYP11B1, and IL7, which have not been mapped on the cattle genome, are likely to be present on cattle chromosome 14. It also shows by comparative genome analysis that a large segment of human chromosome 8q is highly conserved in sheep chromosome 9 and cattle chromosome 14. Based on these data, we propose that sheep chromosome 9 be recognised as the equivalent of cattle chromosome 14.
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