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Publication : Metabolic control of gluconeogenesis in transgenic mice: regulation of the phosphoenolpyruvate carboxykinase gene.

First Author  Wolf G Year  1994
Journal  Nutr Rev Volume  52
Issue  8 Pt 1 Pages  275-7
PubMed ID  7970291 Mgi Jnum  J:20900
Mgi Id  MGI:68962 Doi  10.1111/j.1753-4887.1994.tb01456.x
Citation  Wolf G (1994) Metabolic control of gluconeogenesis in transgenic mice: regulation of the phosphoenolpyruvate carboxykinase gene. Nutr Rev 52(8 Pt 1):275-7
abstractText  Diet and the effect of hormones were studied in transgenic mice bearing a part of the promoter of the gene for the gluconeogenic enzyme phosphoenolpyruvate carboxykinase. The domains of the gene promoter involved in tissue specificity, development, and response to diet were identified by analysis of expression of the mutated gene. Important differences were uncovered between results from earlier cell culture experiments and the results from more physiologic responses of the transgenic animals.
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