| First Author | Kirschner MA | Year | 1994 |
| Journal | Genomics | Volume | 22 |
| Issue | 3 | Pages | 631-3 |
| PubMed ID | 8001975 | Mgi Jnum | J:19872 |
| Mgi Id | MGI:67995 | Doi | 10.1006/geno.1994.1437 |
| Citation | Kirschner MA, et al. (1994) The mouse and human excitatory amino acid transporter gene (EAAT1) maps to mouse chromosome 15 and a region of syntenic homology on human chromosome 5. Genomics 22(3):631-3 |
| abstractText | The gene for human excitatory amino acid transporter (EAAT1) was localized to the distal region of human chromosome 5p13 by in situ hybridization of metaphase chromosome spreads. Interspecific back-cross analysis identified the mouse Eaat1 locus in a region of 5p13 homology on mouse chromosome 15. Markers that are linked with EAAT1 on both human and mouse chromosomes include the receptors for leukemia inhibitory factor, interleukin-7, and prolactin. The Eaat1 locus appears not to be linked to the epilepsy mutant stg locus, which is also on chromosome 15. The EAAT1 locus is located in a region of 5p deletions that have been associated with mental retardation and microcephaly. |
