| First Author | Quaderi NA | Year | 1994 |
| Journal | Genomics | Volume | 22 |
| Issue | 3 | Pages | 648-51 |
| PubMed ID | 8001979 | Mgi Jnum | J:19877 |
| Mgi Id | MGI:68000 | Doi | 10.1006/geno.1994.1442 |
| Citation | Quaderi NA, et al. (1994) Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome. Genomics 22(3):648-51 |
| abstractText | The methyl CpG binding proteins (MeCP1 and MeCP2) are a class of proteins that bind to templates containing symmetrically methylated CpGs. Using an interspecific backcross segregating a number of X-linked markers, we have localized the Mecp2 gene in mouse to the X chromosome close to the microsatellite marker DXMit1. Detailed physical mapping utilizing an available YAC contig encompassing the DXMit1 locus has localized the Mecp2 gene to a 40-kb region between the L1cam and the Rsvp loci, indicating the probable position of a homologue on the human X chromosome. |
