| First Author | Shinohara T | Year | 1994 |
| Journal | Genomics | Volume | 23 |
| Issue | 3 | Pages | 704-6 |
| PubMed ID | 7851902 | Mgi Jnum | J:21107 |
| Mgi Id | MGI:69152 | Doi | 10.1006/geno.1994.1562 |
| Citation | Shinohara T, et al. (1994) Structure and chromosomal localization of the human PD-1 gene (PDCD1). Genomics 23(3):704-6 |
| abstractText | A cDNA encoding mouse PD-1, a member of the immunoglobulin superfamily was previously isolated from apoptosis-induced cells by subtractive hybridization. To determine the structure and chromosomal location of the human PD-1 gene, we screened a human T cell cDNA library by mouse PD-1 probe and isolated a cDNA coding for the human PD-1 protein. The deduced amino acid sequence of human PD-1 was 60% identical to the mouse counterpart, and a putative tyrosine kinase-association motif was well conserved. The human PD-1 gene was mapped to 2q37.3 by chromosomal in situ hybridization. |
