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Publication : Production of interleukin-3 by murine central nervous system neurons.

First Author  Konishi Y Year  1994
Journal  Neurosci Lett Volume  182
Issue  2 Pages  271-4
PubMed ID  7715825 Mgi Jnum  J:23030
Mgi Id  MGI:70659 Doi  10.1016/0304-3940(94)90814-1
Citation  Konishi Y, et al. (1994) Production of interleukin-3 by murine central nervous system neurons. Neurosci Lett 182(2):271-4
abstractText  We examined expression and production of interleukin-3 (IL-3) mRNA and IL-3 protein in mouse primary cultured neurons and glia by the reverse transcription and polymerase chain reaction and a bioassay using an IL-3-dependent cell line. IL-3 mRNA was demonstrated mainly in hippocampal neurons but not in glia, while a small but definite production of bioactive IL-3 was detected in septal and hippocampal neuronal cultures. Thus, endogenous IL-3 might be produced by certain neurons in situ.
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