| First Author | Suter U | Year | 1995 |
| Journal | J Neurosci Res | Volume | 40 |
| Issue | 2 | Pages | 145-51 |
| PubMed ID | 7745607 | Mgi Jnum | J:22869 |
| Mgi Id | MGI:70757 | Doi | 10.1002/jnr.490400202 |
| Citation | Suter U, et al. (1995) Peripheral myelin protein 22: facts and hypotheses. J Neurosci Res 40(2):145-51 |
| abstractText | Mutations affecting the peripheral myelin protein 22 (PMP22) gene are associated with inherited motor and sensory neuropathies in mouse (Trembler and Trembler-J) and human (Charcot-Marie-Tooth disease type 1A and Dejerine-Sottas syndrome). Although genetic studies have established a critical role of PMP22 in the formation and/or maintenance of myelin in the peripheral nervous system, the biological function of PMP22 in myelin and in non-myelin forming cells remains largely enigmatic. In this Mini-Review, we will summarize the current knowledge about PMP22 and discuss its hypothetical function(s) in a broad context. |
