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Publication : GLUT-1 glucose transporter is localized heterogeneously within the microvessels of the mouse hippocampus.

First Author  Kawamoto S Year  1995
Journal  Acta Histochem Volume  97
Issue  1 Pages  105-11
PubMed ID  7771180 Mgi Jnum  J:24049
Mgi Id  MGI:71797 Doi  10.1016/S0065-1281(11)80211-4
Citation  Kawamoto S, et al. (1995) GLUT-1 glucose transporter is localized heterogeneously within the microvessels of the mouse hippocampus. Acta Histochem 97(1):105-11
abstractText  We investigated the distribution of the glucose transporter protein within the microvessels in the mouse hippocampus by immunohistochemical methods with an anti-rat brain glucose transporter 1 (GLUT-1) and confocal laser scanning microscopy. All intraparenchymal microvessels in the hippocampus showed intensive immunoreactivity and a heterogeneous distribution of GLUT-1 was seen in the microvessels. These data may suggest that glucose could be heterogeneously incorporated into the endothelial cells of the cerebral microvessels, and therefore morphological and physiological differences may be present among the endothelial cells.
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