| First Author | McNeil A | Year | 1995 |
| Journal | Infect Immun | Volume | 63 |
| Issue | 7 | Pages | 2770-2 |
| PubMed ID | 7790097 | Mgi Jnum | J:27807 |
| Mgi Id | MGI:75290 | Doi | 10.1128/iai.63.7.2770-2772.1995 |
| Citation | McNeil A, et al. (1995) Salmonella typhimurium displays normal invasion of mice with defective epidermal growth factor receptors. Infect Immun 63(7):2770-2 |
| abstractText | The role of the epidermal growth factor (EGF) receptor in cell invasion by Salmonella typhimurium was examined in vitro and in vivo by using waved-2 mice which express an EGF receptor with reduced kinase activity. S. typhimurium invaded fibroblasts from waved-2 mice as efficiently as fibroblasts from wild-type control animals. In vivo, S. typhimurium both invaded the gastrointestinal tract and penetrated through to the spleen of waved-2 mice. Our studies suggest that the EGF receptor has only a limited role, if any, in cell invasion by S. typhimurium. |
