First Author | Gough NM | Year | 1995 |
Journal | Mamm Genome | Volume | 6 |
Issue | 4 | Pages | 255-6 |
PubMed ID | 7613029 | Mgi Jnum | J:24374 |
Mgi Id | MGI:72140 | Doi | 10.1007/BF00352411 |
Citation | Gough NM, et al. (1995) Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK. Mamm Genome 6(4):255-6 |
abstractText | We have mapped the gene encoding the murine RYK growth factor receptor protein tyrosine kinase by genetic linkage analysis with recombinant inbred strains of mouse. Two distinct Ryk loci (Ryk-1 and Ryk-2) were identified. Ryk-1 mapped to Chromosome (Chr) 9, whereas Ryk-2 mapped to Chr 12. A similar arrangement of RYK-related loci was previously determined in the human. Synteny has already been established between murine Chr 9 in the region of Ryk-1, and human chromosome 3q11-12, the location of the human RYK-1 gene. However, the Ryk-2/RYK-2 loci on murine Chr 12 and human Chr 17p13.3 define a new region of synteny. |