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Publication : Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK.

First Author  Gough NM Year  1995
Journal  Mamm Genome Volume  6
Issue  4 Pages  255-6
PubMed ID  7613029 Mgi Jnum  J:24374
Mgi Id  MGI:72140 Doi  10.1007/BF00352411
Citation  Gough NM, et al. (1995) Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK. Mamm Genome 6(4):255-6
abstractText  We have mapped the gene encoding the murine RYK growth factor receptor protein tyrosine kinase by genetic linkage analysis with recombinant inbred strains of mouse. Two distinct Ryk loci (Ryk-1 and Ryk-2) were identified. Ryk-1 mapped to Chromosome (Chr) 9, whereas Ryk-2 mapped to Chr 12. A similar arrangement of RYK-related loci was previously determined in the human. Synteny has already been established between murine Chr 9 in the region of Ryk-1, and human chromosome 3q11-12, the location of the human RYK-1 gene. However, the Ryk-2/RYK-2 loci on murine Chr 12 and human Chr 17p13.3 define a new region of synteny.
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