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Publication : Expression of protein kinase C delta gene in germ cells.

First Author  Um JY Year  1995
Journal  J Urol Volume  154
Issue  3 Pages  1237-40
PubMed ID  7637094 Mgi Jnum  J:28857
Mgi Id  MGI:76389 Citation  Um JY, et al. (1995) Expression of protein kinase C delta gene in germ cells. J Urol 154(3):1237-40
abstractText  PURPOSE: To investigate the biological functions of protein kinase C delta (PKC delta) in spermatogenesis. MATERIALS AND METHODS: We examined PKC delta transcript in mouse testis by means of in situ hybridization and Northern blotting. RESULTS: In testes of normal mice, signals of PKC delta gene expression were detected specifically at the spermatid stage. The PKC delta gene was weakly expressed in 8-week-old mice and highly expressed by 12 weeks. However, the expression was not detected in testes of germ cell-deficient W/Wv mice even at 12 weeks. CONCLUSIONS: Protein kinase C delta gene expression may be controlled by specific developmental processes and PKC delta may play a role in spermatogenesis.
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