First Author | Um JY | Year | 1995 |
Journal | J Urol | Volume | 154 |
Issue | 3 | Pages | 1237-40 |
PubMed ID | 7637094 | Mgi Jnum | J:28857 |
Mgi Id | MGI:76389 | Citation | Um JY, et al. (1995) Expression of protein kinase C delta gene in germ cells. J Urol 154(3):1237-40 |
abstractText | PURPOSE: To investigate the biological functions of protein kinase C delta (PKC delta) in spermatogenesis. MATERIALS AND METHODS: We examined PKC delta transcript in mouse testis by means of in situ hybridization and Northern blotting. RESULTS: In testes of normal mice, signals of PKC delta gene expression were detected specifically at the spermatid stage. The PKC delta gene was weakly expressed in 8-week-old mice and highly expressed by 12 weeks. However, the expression was not detected in testes of germ cell-deficient W/Wv mice even at 12 weeks. CONCLUSIONS: Protein kinase C delta gene expression may be controlled by specific developmental processes and PKC delta may play a role in spermatogenesis. |