| First Author | Cox DA | Year | 1995 |
| Journal | Cell Biol Int | Volume | 19 |
| Issue | 5 | Pages | 357-71 |
| PubMed ID | 7640653 | Mgi Jnum | J:26894 |
| Mgi Id | MGI:74321 | Doi | 10.1006/cbir.1995.1082 |
| Citation | Cox DA (1995) Transforming growth factor-beta 3. Cell Biol Int 19(5):357-71 |
| abstractText | Transforming Growth Factor-Beta (TGF-beta) is the general name for a family of naturally-occurring polypeptides which have multiple regulatory effects on cell proliferation and differentiation. Over the last decade it has become apparent that TGF-betas can be produced by most cell types and exert a wide range of effects in a context-dependent autocrine, paracrine or endocrine fashion via interactions with distinct receptors on the cell surface. This review summarizes current knowledge concerning the molecular and cellular biology of TGF-beta 3, the most recently described mammalian isoform, and focuses on those physiological actions which may lead to clinical applications, particularly in the indication areas of wound healing and chemoprotection. |
