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Publication : Nonoverlapping expression of Cx43 and Cx26 in the mouse placenta and decidua: a pattern of gap junction gene expression differing from that in the rat.

First Author  Pauken CM Year  1995
Journal  Mol Reprod Dev Volume  41
Issue  2 Pages  195-203
PubMed ID  7654373 Mgi Jnum  J:26125
Mgi Id  MGI:73747 Doi  10.1002/mrd.1080410210
Citation  Pauken CM, et al. (1995) Nonoverlapping expression of Cx43 and Cx26 in the mouse placenta and decidua: a pattern of gap junction gene expression differing from that in the rat. Mol Reprod Dev 41(2):195-203
abstractText  We characterized the expression of two gap junction genes (Cx26 and Cx43) in the mouse decidua and placenta. In the decidua, in situ hybridization analysis and immunostaining studies revealed a high level of Cx43 expression. In contrast, Cx26 expression was not detected. Analysis of the placenta revealed that both Cx43 and Cx26 transcripts are expressed, but in nonoverlapping cell populations. Cx26 transcripts were observed only in the labyrinthine trophoblast layer of the placenta, a tissue of ectoplacental cone derivation. In contrast, no Cx43 transcripts were found in the placenta proper, but only in the maternally derived decidual cap covering the placenta. These results, in conjunction with previous observations in the mouse and rat, indicate that there may be species-specific differences in the pattern of Cx43/Cx26 expression in the placenta and decidua.
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