| First Author | Hume DA | Year | 1995 |
| Journal | Br J Haematol | Volume | 90 |
| Issue | 4 | Pages | 939-42 |
| PubMed ID | 7669676 | Mgi Jnum | J:28078 |
| Mgi Id | MGI:75708 | Doi | 10.1111/j.1365-2141.1995.tb05220.x |
| Citation | Hume DA, et al. (1995) Detection of c-fms protooncogene in early mouse embryos by whole mount in situ hybridization indicates roles for macrophages in tissue remodelling. Br J Haematol 90(4):939-42 |
| abstractText | The c-fms protoncogene which encodes the receptor for macrophage colony-stimulating factor (CSF-1) was localized in the developing mouse embryo by whole in situ hybridization. c-fms was expressed first in placental trophoblasts. Around 9.5 dpc, isolated c-fms-positive cells became detectable in the yolk sac and by 10.5 dpc large numbers were detectable throughout the embryo. The localization of c-fms expression was consistent with its restriction to macrophages, and with the location of those macrophages in sites of tissue turnover and extensive cell death. |
