| First Author | Aldaz CM | Year | 1995 |
| Journal | Cytogenet Cell Genet | Volume | 71 |
| Issue | 3 | Pages | 253-6 |
| PubMed ID | 7587388 | Mgi Jnum | J:29705 |
| Mgi Id | MGI:77230 | Doi | 10.1159/000134121 |
| Citation | Aldaz CM, et al. (1995) Colocalization of the rat homolog of the von Hippel Lindau (Vhl) gene and the plasma membrane Ca++ transporting ATPase isoform 2 (Atp2b2) gene to rat chromosome bands 4q41.3-->42.1. Cytogenet Cell Genet 71(3):253-6 |
| abstractText | Using fluorescence in situ hybridization, we localized the rat homolog of the von Hippel-Lindau gene (Vhl) to rat chromosome band 4q41.3-->q42.1. We also mapped the gene encoding the plasma membrane Ca(++)-transporting ATPase isoform 2(Atp2b2) to the same chromosome subregion. These two genes together with Raf1 appear to be members of a large syntenic gene cluster that maps to human chromosome bands 3p25-->p26, mouse chromosome bands 6 C3-->E, and rat chromosome bands 4q41-->q42. Cytogenetic analysis of NRK 52E cells derived from immortalized normal rat kidney epithelial cells revealed an inverted duplication of the region containing this gene cluster. |
