| First Author | Filali M | Year | 1996 |
| Journal | J Comp Physiol A | Volume | 178 |
| Issue | 1 | Pages | 101-4 |
| PubMed ID | 8568721 | Mgi Jnum | J:31092 |
| Mgi Id | MGI:78561 | Doi | 10.1007/BF00189594 |
| Citation | Filali M, et al. (1996) Spontaneous alternation, motor activity, and spatial learning in hot-foot mutant mice. J Comp Physiol [A] 178(1):101-4 |
| abstractText | Hot-foot mutant mice, characterized by defective innervation of Purkinje cells and an ataxic gait, were less active than normal mice in a T-maze. In spontaneous alternation testing with either single or multiple trials, hot-foot mutants, contrary to normal mice, did not alternate above chance. Moreover, the mutants had a higher number of errors and higher escape latencies in a water-filled Z-maze. These results indicate that in addition to motor coordination deficits, these cerebellar mutants have deficits in spatial learning and perseverate choices of maze arms. |
