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Publication : A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.

First Author  Puliti A Year  1995
Journal  Mamm Genome Volume  6
Issue  11 Pages  763-8
PubMed ID  8597630 Mgi Jnum  J:29847
Mgi Id  MGI:77371 Doi  10.1007/BF00539000
Citation  Puliti A, et al. (1995) A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus. Mamm Genome 6(11):763-8
abstractText  Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra- and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking this locus.
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