First Author | Puliti A | Year | 1995 |
Journal | Mamm Genome | Volume | 6 |
Issue | 11 | Pages | 763-8 |
PubMed ID | 8597630 | Mgi Jnum | J:29847 |
Mgi Id | MGI:77371 | Doi | 10.1007/BF00539000 |
Citation | Puliti A, et al. (1995) A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus. Mamm Genome 6(11):763-8 |
abstractText | Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra- and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking this locus. |