| First Author | McGraw DW | Year | 1996 |
| Journal | Biochim Biophys Acta | Volume | 1305 |
| Issue | 3 | Pages | 135-8 |
| PubMed ID | 8597598 | Mgi Jnum | J:31755 |
| Mgi Id | MGI:79241 | Doi | 10.1016/0167-4781(95)00227-8 |
| Citation | McGraw DW, et al. (1996) Structural and functional analysis of the 5'-flanking region of the rat beta 2-adrenergic receptor gene. Biochim Biophys Acta 1305(3):135-8 |
| abstractText | We have analyzed 3.4 kb of DNA from the 5'-flanking region of the rat beta 2-adrenergic receptor gene and assessed its promoter activity in A549 cells, a human lung adenocarcinoma cell line. A single transcription start site was identified approx. 223 bp upstream of the ATG start codon. A549 cells were transfected with luciferase reporter plasmids containing segments of the rat beta 2-adrenergic receptor 5'-flanking region. Our results suggest that both positive and negative cis-acting regulatory sequences are present in the 5'-flanking region of the rat beta 2-adrenergic receptor gene. |
