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Publication : Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes.

First Author  Mahata SK Year  1996
Journal  Genomics Volume  33
Issue  1 Pages  135-9
PubMed ID  8617499 Mgi Jnum  J:32418
Mgi Id  MGI:79913 Doi  10.1006/geno.1996.0171
Citation  Mahata SK, et al. (1996) Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes. Genomics 33(1):135-9
abstractText  Chromogranin A, chromogranin B, and secreto-granin II, members of the chromogranin/secretogranin secretory protein family, are overexpressed in some human hereditary maladies and may have arisen, in part, from common ancestor genes. To understand better the mammalian chromosomal dispersion of this gene family and to facilitate studies of these genes in human illnesses and their animal models, we positioned the locus of each member in the rat, mouse, and human genomes. Our results indicate that each locus lies in a region of locally syntenic chromosomal homology across the three species. (C) 1996 Academic Press, Inc.
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