| First Author | Ohno K | Year | 1996 |
| Journal | Exp Anim | Volume | 45 |
| Issue | 1 | Pages | 71-5 |
| PubMed ID | 8689583 | Mgi Jnum | J:31337 |
| Mgi Id | MGI:78840 | Doi | 10.1538/expanim.45.71 |
| Citation | Ohno K, et al. (1996) Mapping of the dilute-opisthotonus (dop) gene on chromosome 8 of the rat. Exp Anim 45(1):71-5 |
| abstractText | The rat dilute-opisthotonus (dop) autosomal recessive gene, causing ataxia and coat color dilution, was mapped on chromosome 8 by PCR-amplified microsatellite markers. To facilitate the linkage analysis, an intersubspecific cross with a Japanese wild rat strain was used. The recombination frequencies were 12.8% between Apoc3 and dop, and 32.1% between dop and Mylc1v. The following order of three genes is proposed; Apoc3-dop-Mylc1v. This mutation appears to be homologous to dilute-lethal (d1) of the mouse in terms of clinical symptoms, coat color effect and chromosomal location of the gene loci. Key words: ataxic mutant rat, dilute-opisthotonus (dop), gene mapping. |
