First Author | Pan YX | Year | 1996 |
Journal | Gene | Volume | 171 |
Issue | 2 | Pages | 255-60 |
PubMed ID | 8666282 | Mgi Jnum | J:33632 |
Mgi Id | MGI:81110 | Doi | 10.1016/0378-1119(95)00890-x |
Citation | Pan YX, et al. (1996) Structure and characterization of the gene encoding a mouse kappa3-related opioid receptor. Gene 171(2):255-60 |
abstractText | A genomic clone comprising the entire cDNA sequence encoding a mouse kappa(3)-related opioid receptor (KOR-3) was isolated by screening a mouse genomic library with a radiolabeled mouse KOR-3 cDNA probe. Sequence analysis of the genomic clone indicates that the KOR-3 gene contains five exons separated by four introns. The transcription start point (tsp) of KOR-3 was mapped by primer extension analysis of RNAs synthesized either in vivo or in vitro. A TATA-box and several potential regulatory elements, including five GRE sites, four NF-E1 binding sites and one MRE site, are present in the 2 kb of 5'-flanking region. A putative poly(A) signal (AATAAA) is found in the 3'- flanking region. |