| First Author | Hansen JD | Year | 1996 |
| Journal | Immunogenetics | Volume | 44 |
| Issue | 3 | Pages | 203-11 |
| PubMed ID | 8662087 | Mgi Jnum | J:34489 |
| Mgi Id | MGI:81945 | Doi | 10.1007/BF02602586 |
| Citation | Hansen JD, et al. (1996) The recombination activating gene 2 (RAG2) of the rainbow trout Oncorhynchus mykiss. Immunogenetics 44(3):203-11 |
| abstractText | We have previously described the isolation and expression of RAG1 in trout to provide an initial understanding regarding the tissues involved in V(D)J recombination of antigen receptors in this teleost. Here we report that the recombination activating gene 2 (RAG2) of rainbow trout has now been cloned and characterized. The rainbow trout genomic RAG2 gene (1602 base pairs) displays an average of 60% and 75% similarity at the nucleotide and amino acid level when compared with clones from other species and was found to contain an acidic region in the carboxyl terminal end, which is typical of RAG2 sequences. The proximity of RAG1 and -2 within this teleost is similar to that found in other vertebrates. The genes are convergently transcribed and share a 3' untranslated (UT) region [2. 8 kilobases (kb)] which is much shorter than that found in higher |
