| First Author | Bruch J | Year | 1996 |
| Journal | Cytogenet Cell Genet | Volume | 73 |
| Issue | 3 | Pages | 164-7 |
| PubMed ID | 8697800 | Mgi Jnum | J:34723 |
| Mgi Id | MGI:82177 | Doi | 10.1159/000134331 |
| Citation | Bruch J, et al. (1996) Mapping of type I loci from human chromosome 7 reveals segments of conserved synteny on pig chromosomes 3, 9, and 18. Cytogenet Cell Genet 73(3):164-7 |
| abstractText | We have mapped in the pig (Sus scrofa) the genes for zona pellucida glycoprotein 3 (ZP3), erythropoietin (EPO), and malate dehydrogenase 2 (MDH2) by somatic cell hybrid analysis in the pig genome. Previously, the gene for the T-cell receptor beta cluster (TCRB) was assigned to SSC 18 and that for interleukin 6 (IL6) to SSC 9. However, statistical analysis of mapping data for ZP3, EPO, and MDH2 did not discriminate between SSC 9 and SSC 3. Porcine-specific PCR primers for ZP3 and IL6 were used to isolate probes from porcine YAC libraries. These two genes were mapped by FISH to porcine chromosome regions 3pter --> p15 (ZP3) and 9q14 --> q15 (IL6). Comparative mapping considerations permit the tentative assignment of porcine EPO and MDH2 to 3pter --> p15. |
