| First Author | Katsura M | Year | 1995 |
| Journal | Brain Res Mol Brain Res | Volume | 34 |
| Issue | 2 | Pages | 355-9 |
| PubMed ID | 8750843 | Mgi Jnum | J:30589 |
| Mgi Id | MGI:78088 | Doi | 10.1016/0169-328x(95)00192-u |
| Citation | Katsura M, et al. (1995) Ethanol stimulates diazepam binding inhibitor (DBI) mRNA expression in primary cultured neurons. Brain Res Mol Brain Res 34(2):355-9 |
| abstractText | Changes in expression of diazepam binding inhibitor (DBI) mRNA in cerebral cortical neurons following long-term ethanol (EtOH) exposure were examined. A significant increase in DBI mRNA expression was observed by the exposure of neurons to 50 mM EtOH for up to 5 days and to EtOH (1-100 mM) for 3 days. These EtOH-induced increases in DBI mRNA expression were further elevated after the additional cultivation of neurons under EtOH-free condition. beta-Actin mRNA expression was not altered by similar EtOH treatments. These results indicate that EtOH possesses the activity to increase the expression of DBI mRNA in cerebral cortical neurons. |
