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Publication : Localization of novel receptor tyrosine kinase genes of the eph family, MDK1 and its splicing variant, in the developing mouse nervous system.

First Author  Mori T Year  1995
Journal  Brain Res Mol Brain Res Volume  34
Issue  1 Pages  154-60
PubMed ID  8750872 Mgi Jnum  J:29756
Mgi Id  MGI:77275 Doi  10.1016/0169-328x(95)00154-k
Citation  Mori T, et al. (1995) Localization of novel receptor tyrosine kinase genes of the eph family, MDK1 and its splicing variant, in the developing mouse nervous system. Brain Res Mol Brain Res 34(1):154-60
abstractText  In the course of studies to identify new members of the eph family of receptor tyrosine kinases, MDK1 and one of its splicing variants lacking a kinase domain, MDK1-T1, were identified. To gain insight into the functions of these subtypes, expression patterns of their mRNAs in the developing mouse nervous system were examined by Northern blotting and in situ hybridization histochemistry. Colocalization of their mRNAs was observed, but the levels of expression of each mRNA were developmentally regulated. These findings suggest functional differences between full-length and truncated forms of MDK1 receptor tyrosine kinase.
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