| First Author | Ogura K | Year | 1996 |
| Journal | Biochem Biophys Res Commun | Volume | 225 |
| Issue | 3 | Pages | 932-8 |
| PubMed ID | 8780713 | Mgi Jnum | J:35099 |
| Mgi Id | MGI:82553 | Doi | 10.1006/bbrc.1996.1274 |
| Citation | Ogura K, et al. (1996) Cloning and expression of cDNA for O-acetylation of GD3 ganglioside. Biochem Biophys Res Commun 225(3):932-8 |
| abstractText | O-acetylated sialic acids of glycoproteins and gangliosides show cell type-specific and developmentally regulated expression in various systems and sometimes reappear as oncofetal antigens. O-acetylation of sialic acids may influence cell-cell interactions mediated by the sialic acid-binding lectins. Here we describe the molecular cloning and sequencing of a gene that produces O-acetyl disialoganglioside (O-acetyl GD3). Expression analysis showed that this gene product participates the O-acetylation of GD3 ganglioside sialic acid. The deduced amino acid sequence of the product was found to be similar to the milk fat globule membrane glycoprotein. |
