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Publication : Regional localization of rat and mouse protein-tyrosine phosphatase PTP alpha/LRP gene (Ptpra) by fluorescence in situ hybridization.

First Author  Saadat M Year  1995
Journal  Jpn J Genet Volume  70
Issue  6 Pages  669-74
PubMed ID  8790445 Mgi Jnum  J:31919
Mgi Id  MGI:79423 Doi  10.1266/jjg.70.669
Citation  Saadat M, et al. (1995) Regional localization of rat and mouse protein-tyrosine phosphatase PTP alpha/LRP gene (Ptpra) by fluorescence in situ hybridization. Jpn J Genet 70(6):669-74
abstractText  Protein tyrosine phosphatases (PTPases) negatively regulate the effect(s) of protein tyrosine kinases and are implicated in the regulation of a variety of biological events including cell activation, differentiation, and neoplastic transformation. To gain insight into the role(s) of the PTPases, we mapped the gene encoding for the widely expressed receptor-like protein tyrosine phosphatase PTP alpha/LRP (locus symbol Ptpra) to rat chromosome 3q36 and mouse chromosome 2G by fluorescence in situ hybridization method. These results indicate that there is a conserved syntenic group between human 20p13, rat 3q36, and mouse 2G.
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