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Publication : Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13.

First Author  Warren G Year  1996
Journal  Genomics Volume  31
Issue  2 Pages  234-7
PubMed ID  8824807 Mgi Jnum  J:31184
Mgi Id  MGI:78668 Doi  10.1006/geno.1996.0037
Citation  Warren G, et al. (1996) Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13. Genomics 31(2):234-7
abstractText  Transcription factors are a major determinant of developmental fate. The chromosomal localization of the genes encoding these proteins provides important information that can link them to known genetic abnormalities. Here, we report the mapping of the mouse gene for transcription factor AP-2, a protein that has been implicated in human oncogenesis. Using FISH, we have mapped the gene encoding the transcription factor AP-2, Tcfap2, to mouse Chromosome 13A5-B1. We have also extended this analysis by placing Tcfap2 on the mouse genetic map, and we discuss the candidate mouse mutations that map in the vicinity of this transcription factor. (C) 1996 Academic Press,Inc.
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