| First Author | Mohandas TK | Year | 1995 |
| Journal | Genomics | Volume | 30 |
| Issue | 3 | Pages | 594-7 |
| PubMed ID | 8825647 | Mgi Jnum | J:30584 |
| Mgi Id | MGI:78083 | Doi | 10.1006/geno.1995.1281 |
| Citation | Mohandas TK, et al. (1995) Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7. Genomics 30(3):594-7 |
| abstractText | The gene encoding the tight junction (zonula occludens) protein, TJP1, was mapped to human chromosome 15q13 by fluorescence in situ hybridization (FISH) using a cDNA probe. The Jackson Laboratory backcross DNA panel derived from the cross (C57BL/6JEi x SPRET/Ei) F1 females x SPRET/ Ei males was used to map the mouse Tjp1 to chromosome 7 near position 30 on the Chromosome Committee Map, a region with conserved homology to human chromosome 15q13. FISH studies on metaphases from patients with the Prader-Willi (PWS) or the Angelman syndrome (AS) showed that TJP1 maps close but distal to the PWS/AS chromosome region. (C) 1995 Academic Press, Inc. |
