First Author | Reines D | Year | 1996 |
Journal | Trends Biochem Sci | Volume | 21 |
Issue | 9 | Pages | 351-5 |
PubMed ID | 8870500 | Mgi Jnum | J:35409 |
Mgi Id | MGI:82858 | Citation | Reines D, et al. (1996) The RNA polymerase II general elongation factors. Trends Biochem Sci 21(9):351-5 |
abstractText | Synthesis of eukaryotic messenger RNA by RNA polymerase II is governed by the concerted action of a set of general transcription factors that control the activity of polymerase during both the initiation and elongation stages of transcription. To date, five general elongation factors [P-TEFb, SII, TFIIF, Elongin (SIII) and ELL] have been defined biochemically. Here, we discuss these transcription factors and their roles in controlling the activity of the RNA polymerase II elongation complex. |