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Publication : The RNA polymerase II general elongation factors.

First Author  Reines D Year  1996
Journal  Trends Biochem Sci Volume  21
Issue  9 Pages  351-5
PubMed ID  8870500 Mgi Jnum  J:35409
Mgi Id  MGI:82858 Citation  Reines D, et al. (1996) The RNA polymerase II general elongation factors. Trends Biochem Sci 21(9):351-5
abstractText  Synthesis of eukaryotic messenger RNA by RNA polymerase II is governed by the concerted action of a set of general transcription factors that control the activity of polymerase during both the initiation and elongation stages of transcription. To date, five general elongation factors [P-TEFb, SII, TFIIF, Elongin (SIII) and ELL] have been defined biochemically. Here, we discuss these transcription factors and their roles in controlling the activity of the RNA polymerase II elongation complex.
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