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Publication : Craniofacial defects in AP-2 null mutant mice.

First Author  Morriss-Kay GM Year  1996
Journal  Bioessays Volume  18
Issue  10 Pages  785-8
PubMed ID  8885715 Mgi Jnum  J:36666
Mgi Id  MGI:84093 Doi  10.1002/bies.950181004
Citation  Morriss-Kay GM (1996) Craniofacial defects in AP-2 null mutant mice. Bioessays 18(10):785-8
abstractText  AP-2 is a recent significant addition to the list of transcription factors that have been demonstrated by targeted gene disruption to be essential for normal development. Two recent reports of AP-2 null mutant mice((1,2)) indicate that AP-2 holds a key position in the network of genes and proteins controlling developmental pattern and morphogenesis, and that it is particularly important for development of the cranial region and for midline fusions.
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