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Publication : Nerve growth factor in the developing craniofacial region of the mouse embryo.

First Author  Louryan S Year  1995
Journal  Eur J Morphol Volume  33
Issue  5 Pages  415-9
PubMed ID  8907554 Mgi Jnum  J:32054
Mgi Id  MGI:79557 Citation  Louryan S, et al. (1995) Nerve growth factor in the developing craniofacial region of the mouse embryo. Eur J Morphol 33(5):415-9
abstractText  Nerve growth factor (NGF), demonstrated by immunohistochemistry, appears during craniofacial development of the mouse in several embryonic tissues. First, NGF is present in the neural and placodic tissues of early embryos. At later stages, NGF staining appears in premuscular and precartilaginous blastemata, as well as in the tooth germs. The presence of NGF in muscular primordia is probably in relation with its putative trophic effect on target tissues. However, cartilaginous expression of NGF supports the view that this molecule could play a role in the regulation of preskeletal differentiation.
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