| First Author | Mertens B | Year | 1996 |
| Journal | Gene | Volume | 176 |
| Issue | 1-2 | Pages | 273-4 |
| PubMed ID | 8918267 | Mgi Jnum | J:36464 |
| Mgi Id | MGI:83891 | Doi | 10.1016/0378-1119(96)00252-1 |
| Citation | Mertens B, et al. (1996) The nucleotide sequence of the bovine interleukin-5-encoding cDNA. Gene 176(1-2):273-4 |
| abstractText | The nucleotide (nt) sequence encoding the bovine homologue of interleukin-5 (boIL-5) was determined. Total cDNA generated from stimulated bovine peripheral blood lymphocytes was used to amplify the boIL-5 gene using primers based on the 5' and 3' untranslated regions of the ovine IL-5 cDNA sequence. The boIL-5 coding sequence is 405 bp long, coding for a 15.2 kDa precursor protein of 134 amino acids (aa). Cleavage of a putative signal peptide of 19 aa yields a mature form of 13.1 kDa. Comparisons at the nt level revealed 96%, 81%, 74% and 73% identity with the ovine, human, mouse and rat IL-5 sequences, respectively, and 97%, 66%, 59% and 58% aa identity, respectively. |
