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Publication : The porcine TTR locus maps to chromosome 6q.

First Author  Archibald AL Year  1996
Journal  Anim Genet Volume  27
Issue  5 Pages  351-3
PubMed ID  8930078 Mgi Jnum  J:36924
Mgi Id  MGI:84339 Doi  10.1111/j.1365-2052.1996.tb00977.x
Citation  Archibald AL, et al. (1996) The porcine TTR locus maps to chromosome 6q. Anim Genet 27(5):351-3
abstractText  The sequence of a cDNA clone encoding porcine transthyretin (prealbumin) was used to develop polymorphic markers for the TTR locus. The single-strand conformation polymorphism (SSCP) detected is caused by a silent A/T mutation in the penultimate coding codon and can also be revealed as a SacI restriction fragment length polymorphism (RFLP). The TTR locus was mapped to chromosome 6q by segregation and linkage analysis with these polymorphisms. This assignment confirms the predictions of homology between human chromosome 18 and pig chromosome 6q2 . 5-q2 . 6.
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