| First Author | Takai S | Year | 1996 |
| Journal | Genomics | Volume | 38 |
| Issue | 3 | Pages | 429-31 |
| PubMed ID | 8975722 | Mgi Jnum | J:37705 |
| Mgi Id | MGI:85097 | Doi | 10.1006/geno.1996.0648 |
| Citation | Takai S, et al. (1996) Assignment of the CD45-AP gene to the centromeric end of mouse chromosome 19 and human chromosome 11q13.1-q13.3. Genomics 38(3):429-31 |
| abstractText | CD45-AP is a recently identified phosphorylated protein that specifically associates with the leukocyte-specific transmembrane glycoprotein CD45. The gene for CD45-AP, Ptprcap (protein tyrosine phosphatase, receptor type c polypeptide associated protein), was mapped in mouse by typing the progeny of two multilocus crosses using the mouse CD45-AP cDNA as a Southern hybridization probe, The CD45-AP gene mapped to the centromeric region of Chr 19 proximal to the genes Fth, Cd5, and Pcna-rs. The gene for the human CD45-AP homologue, PTPRCAP, was localized to chromosome band 11q13.1-q13.3 by fluorescence in situ hybridization using human genomic CD45-AP DNA as a hybridization probe, The genetic mapping of the Ptprcap/PTPRCAP genes extends the previously defined synteny conservation of various genes that have been assigned to these regions of the mouse and the human chromosomes. (C) 1996 Academic Press, Inc. |
