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Publication : The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization.

First Author  Egashira M Year  1996
Journal  Cytogenet Cell Genet Volume  72
Issue  2-3 Pages  175-6
PubMed ID  8978766 Mgi Jnum  J:31445
Mgi Id  MGI:78953 Doi  10.1159/000134179
Citation  Egashira M, et al. (1996) The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization. Cytogenet Cell Genet 72(2-3):175-6
abstractText  The human HS1 gene (HCLS1, hematopoietic cell-specific Lyn substrate 1) expressed in human hematopoietic cells encodes a major substrate of protein-tyrosine kinase, p75HS1. This intracellular protein is involved in the signal transduction pathways that initiate at the antigen receptors of both B and T lymphocytes. Fluorescence in situ hybridization using a 2.0-kb cDNA and an 8.0-kb genomic DNA clone of HCLS1 as probes revealed that the gene maps to 3q13.
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