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Publication : Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library.

First Author  Tsui SK Year  1996
Journal  Biochem Genet Volume  34
Issue  9-10 Pages  367-73
PubMed ID  8978909 Mgi Jnum  J:38012
Mgi Id  MGI:85405 Doi  10.1007/BF00554412
Citation  Tsui SK, et al. (1996) Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library. Biochem Genet 34(9-10):367-73
abstractText  A full-length cDNA clone for human 6-phosphogluconate dehydrogenase (PGD) was isolated from a human adult heart cDNA library. The clone encoded an open reading frame of 483 amino acids. When the amino acid sequences of human PGD and sheep PGD were aligned, 94.2% identity between these two proteins was found. Its calculated molecular weight is 53,149 daltons. The predicted isoelectric point is 6.85. When the secondary structure of human PGD was examined by the PROSIS software, 36% alpha-helix and 9% beta-sheet were found.
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