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Publication : Localization of leptin receptor mRNA expression in mouse brain.

First Author  Huang XF Year  1996
Journal  Neuroreport Volume  7
Issue  15-17 Pages  2635-8
PubMed ID  8981437 Mgi Jnum  J:38075
Mgi Id  MGI:85464 Doi  10.1097/00001756-199611040-00045
Citation  Huang XF, et al. (1996) Localization of leptin receptor mRNA expression in mouse brain. Neuroreport 7(15-17):2635-8
abstractText  The distribution of the leptin receptor in the brain of C57 mice was investigated using a non-radioactive in situ hybridization method. Leptin receptor mRNA expression was highest in the arcuate nucleus and median eminence of the hypothalamus, but it was also abundant in hippocampus, primarily in the dentate gyrus and CA1, and was detected at low levels in piriform cortex and the medial margin of the medial habenular nucleus. The localization of leptin receptor-containing neurones in the present study indicates the possibility that the leptin receptor is expressed on neuropeptide Y-containing neurones.
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