| First Author | Botto JM | Year | 1997 |
| Journal | FEBS Lett | Volume | 400 |
| Issue | 2 | Pages | 211-4 |
| PubMed ID | 9001400 | Mgi Jnum | J:37646 |
| Mgi Id | MGI:85037 | Doi | 10.1016/s0014-5793(96)01391-9 |
| Citation | Botto JM, et al. (1997) Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system. FEBS Lett 400(2):211-4 |
| abstractText | This work describes the molecular cloning of a variant isoform of the low-affinity levocabastine-sensitive neurotensin receptor isolated from mouse brain. Although the corresponding mRNA encodes for a 282 amino acid protein unable to bind neurotensin after transient transfection in COS-7 cells, this nonfunctional neurotensin receptor is expressed in cerebral neocortex, cerebellum, olfactory bulb, striatum and hypothalamus with a level similar to that of the full-length low-affinity neurotensin receptor. By contrast, this receptor form is very weakly expressed in mesencephalon and absent in the pituitary, but is the major product in the spinal cord. |
