| First Author | Smith S | Year | 1997 |
| Journal | Trends Genet | Volume | 13 |
| Issue | 1 | Pages | 21-6 |
| PubMed ID | 9009844 | Mgi Jnum | J:37530 |
| Mgi Id | MGI:84922 | Doi | 10.1016/s0168-9525(96)10052-4 |
| Citation | Smith S, et al. (1997) TRF1, a mammalian telomeric protein. Trends Genet 13(1):21-6 |
| abstractText | Telomerase adds TTAGGG repeats onto mammalian chromosome ends, replenishing the terminal sequence loss incurred during DNA replication. This maintenance of telomeric DNA preserves binding sites for telomeric proteins, which form a protective nucleoprotein complex at chromosome ends. The recent isolation of TRF1, the mammalian telomeric-repeat binding factor, should now allow the structure and function of the telomeric complex to be examined in detail. |
