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Publication : mGluR1 mutant mice as a tool to study calcium signalling and multiple innervation in the cerebellum.

First Author  Daniel H Year  1996
Journal  J Physiol Paris Volume  90
Issue  3-4 Pages  171-2
PubMed ID  9116662 Mgi Jnum  J:40114
Mgi Id  MGI:87458 Doi  10.1016/s0928-4257(97)81418-0
Citation  Daniel H, et al. (1996) mGluR1 mutant mice as a tool to study calcium signalling and multiple innervation in the cerebellum. J Physiol Paris 90(3-4):171-2
abstractText  The present study reports that calcium signalling through voltage-gated calcium channels and release from internal stores is impaired in Purkinje cells of mutant mice lacking in GluR1 receptors and that the absence of these receptors also leads to an incomplete regression of multiple innervation in the cerebellum of these animals.
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