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Publication : Cloning of the cDNA coding for rat brain CMP-NeuAc:GD3 alpha2-8 sialyltransferase.

First Author  Zeng G Year  1997
Journal  Gene Volume  187
Issue  1 Pages  131-4
PubMed ID  9073076 Mgi Jnum  J:39136
Mgi Id  MGI:86517 Doi  10.1016/s0378-1119(96)00735-4
Citation  Zeng G, et al. (1997) Cloning of the cDNA coding for rat brain CMP-NeuAc:GD3 alpha2-8 sialyltransferase. Gene 187(1):131-4
abstractText  The cDNA coding for GT3-synthase has been cloned from a rat fetal brain cDNA library. The complete nucleotide sequence and the deduced amino acid sequence of the rat GT3-synthase cDNA were highly homologous to those of the mouse GT3-synthase. Quantitative RT-PCR showed that, as a key enzyme for the synthesis of 'c'-series gangliosides, the expression of GT3-synthase was developmentally regulated in embryonic rat brains.
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